Product Composition & Structure

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Formulation 2 options — component shares are % of the finished formulation
Lyophilized powder for injection primary base: Atrimustine hydrochloride Nitrogen mustard alkylating agent for cancer therapy
ComponentRoleShareSourceable matches
Mannitol Bulking agent/lyoprotectant
75% (70–80)
Atrimustine hydrochloride Active ingredient
15% (10–20)
Water for injection Solvent (residual moisture)
4٫2% (2–5)
Sodium citrate dihydrate Buffer
3٫5% (2–5)
Citric acid monohydrate Buffer
2% (1–3)
Polysorbate 80 Surfactant
0٫3% (0٫1–0٫5)
Solution for intravenous infusion base: Atrimustine hydrochloride Nitrogen mustard alkylating agent for cancer therapy
ComponentRoleShareSourceable matches
Water for injection Solvent
94٫6% (92–97)
Atrimustine hydrochloride Active ingredient
3% (1–5)
Sodium citrate dihydrate Buffer
1% (0٫5–1٫5)
Sodium chloride Tonicity agent
0٫9% (0٫5–1)
Citric acid monohydrate Buffer
0٫5% (0٫2–0٫8)

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kg
Component
Material BASE
Percentage (%): 0%
Required Weight: 0 kg
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