Product Composition & Structure

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Pharmaceutical Products incl. Contraceptives and Vaccines › Antineoplastic agents › Tyrosine kinase inhibitors › Abemaciclib

Abemaciclib

Product ID: 282177
1 materials 1 total parts
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Formulation 1 option — component shares are % of the finished formulation
Abemaciclib tablets (50 mg, 100 mg, 150 mg) primary base: Abemaciclib with excipients for oral tablet Pharmaceutical active ingredient- typically as tablets
ComponentRoleShareSourceable matches
Microcrystalline cellulose Filler/binder
38٫293% (30–40)
Methylcellulose 67% Cellulose/talc 61% Carboxymethylcellulose sodium 61% Used In
Lactose monohydrate Filler
27٫352% (20–30)
Lactitol monohydrate 76% Lactitol dihydrate 70% Lactose 68% Used In
Abemaciclib Active pharmaceutical ingredient
10٫941% (5–15)
Abemaciclib 95% Palbociclib 68% Ribociclib 67% Used In
Croscarmellose sodium Disintegrant
8٫206% (5–10)
Carmellose 67% Carboxymethylcellulose sodium 65% Carboxymethylcellulose/hypromellose 58% Used In
Povidone (PVP K30) Binder
4٫376% (3–5)
Povidone 94% Povidone iodine 77% Polyvinyl alcohol/povidone 72% Used In
Talc Anti-adherent
3٫282% (2–4)
Talc 93% Cellulose/talc 61% Bentonite/potassium alum/talc 58% Used In
Polyvinyl alcohol (PVA) (coating) Film coating
3٫282% (2–4)
Polyvinyl alcohol 95% Polyvinyl alcohol 95% Polyvinyl alcohol films 85% Used In
Titanium dioxide Opacifier/coating
1٫641% (1–2)
Titanium dioxide 90% Titanium oxide 83% Titanium dioxide/zinc oxide 76% Used In
Magnesium stearate Lubricant
1٫094% (0٫5–1٫5)
Magnesium carbonate 56% Magnesium trisilicate 55% Erythromycin stearate 54% Used In
Colloidal silicon dioxide Glidant
1٫094% (0٫5–1٫5)
Silica 64% Minerals 64% Silica gel 60% Used In
Iron oxide yellow Colorant
0٫219% (0٫1–0٫3)
Welding and soldering and brazing supplies 61% Clinical chemistry substrates 60% Iron Fe 60% Used In
Iron oxide red Colorant
0٫219% (0٫1–0٫3)
Welding and soldering and brazing supplies 61% Clinical chemistry substrates 60% Iron Fe 60% Used In