Product Composition & Structure

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Pharmaceutical Products incl. Contraceptives and Vaccines › Antihypertensive drugs › Antihypertensive prostaglandins and pyrazoles and pyrimidines and quinazolines › Macitentan

Macitentan

Product ID: 282214
1 materials 1 total parts
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Formulation 1 option — component shares are % of the finished formulation
Tablet formulation primary base: Macitentan Active pharmaceutical ingredient
ComponentRoleShareSourceable matches
Lactose monohydrate Filler
52٫632% (40–60)
Lactitol monohydrate 76% Lactitol dihydrate 70% Lactose 68% Used In
Microcrystalline cellulose Binder/Diluent
21٫053% (15–25)
Methylcellulose 67% Cellulose/talc 61% Carboxymethylcellulose sodium 61% Used In
Pregelatinized starch Binder
10٫526% (5–15)
Potato flakes/granules 54% Soy flour/polyvidone 51% Pentastarch 51% Used In
Macitentan Active ingredient
5٫263% (2–8)
Macitentan 95% Bosentan 70% Sitaxentan 70% Used In
Croscarmellose sodium Disintegrant
3٫684% (2–5)
Carmellose 67% Carboxymethylcellulose sodium 65% Carboxymethylcellulose/hypromellose 58% Used In
Hypromellose Film coating
3٫158% (2–5)
Hypromellose 92% Carboxymethylcellulose/hypromellose 72% Methylcellulose 69% Used In
Polyethylene glycol Plasticizer
1٫053% (0٫5–2)
Polyethylene glycol 95% Polyethylene glycol 400 84% Polyethylene glycol 400/propylene glycol 79% Used In
Titanium dioxide Opacifier
1٫053% (0٫5–2)
Titanium dioxide 90% Titanium oxide 83% Titanium dioxide/zinc oxide 76% Used In
Magnesium stearate Lubricant
1٫053% (0٫5–2)
Magnesium carbonate 56% Magnesium trisilicate 55% Erythromycin stearate 54% Used In
Colloidal silicon dioxide Glidant
0٫526% (0٫2–1)
Silica 64% Minerals 64% Silica gel 60% Used In